| Tong Tong Wu, Ph.D. | |
| Assistant Professor | Phone: (301) 405-3085 |
| Department of Epidemiology and Biostatistics | Office: 2234B SPH Building |
| University of Maryland | Email:  |
General Information
Dr. Tong Tong Wu received her Ph.D. in Biostatistics from the Department of Biostatistics, UCLA School of Public Health in 2006. She then held a postdoctoral researcher position in the Department of Human Genetics, UCLA when visiting the Department of Statistics at Stanford University. Dr. Wu started as an Assistant Professor in the Department of Epidemiology and Biostatistics in August, 2007.
Dr. Wu is a biostatistician with interests in
- High-dimensional data analysis
- Survival analysis
- Machine learning
- Computational statistics
- Computational biology and statistical genetics
- Longitudinal data analysis
Teaching
- EPIB 651 - Biostatistics II: Fall 2007, Spring 2008, 2009, 2010, 2011, 2012
- EPIB 652 - Categorical Data Analysis: Fall 2007, 2008, 2009, 2010, 2011, 2012
Editorial Boards
- Associate Editor, Annals of Applied Statistics, 2012 - present
Selected Publications
- Tang, C.Y. and Wu, T.T. (2013) Nested Coordinate Descent Algorithms for Empirical Likelihood. Journal of Statistical Computation and Simulation, in press.
- Wu, T.T. and Wang, S. (2012) Doubly Regularized Cox Regression for High-dimensional Survival Data with Group Structures. Statistics and Its Interface, in press.
- Wu, T.T. and Wu, Y. (2012) Nonlinear Vertex Discriminant Analysis with Reproducing Kernels. Statistical Analysis and Data Mining, Volume 5, No 2, 167-176.
- Wu, T.T. (2011) Lasso Penalized Semiparametric Regression on High-Dimensional Recurrent Event Data via Coordinate Descent. Journal of Statistical Computation and Simulation, in press.
- Wu, T.T. and He, X. (2012) Coordinate Ascent for Penalized Semiparametric Regression on High-Dimensional Panel Count Data. Computational Statistics and Data Analysis, Volume 56, No 1, 25-33.
- Wu, T.T., Gong, H., and Clarke, E. (2011) A Transcriptome Analysis by Lasso Penalized Cox Regression for Pancreatic Cancer Survival. Journal of Bioinformatics and Computational Biology, Volume 9, Suppl. 1, 1-11.
- Wu, T.T. and Lange, K. (2010) The MM Alternative to EM. Statistical Science, Volume 25, No 4, 492-505.
- Wu, T.T. and Lange, K. (2010)
Multicategory Vertex Discriminant Analysis for High-Dimensional Data.
Annals of Applied Statistics, Volume 4, No 4, 1698-1721.
Supplementary File: Proof of Proposition 1
R package: VDA - Li, G. and Wu, T.T. (2010) (alphabetic order) Semiparametric Additive Risks Regression for Two-Stage Design Survival Studies. Statistica Sinica, Volume 20, No 4, 1581-1607.
- Wu, T.T., Chen, Y.F., Hastie, T., Sobel, E., and Lange, K. (2009)
Genomewide Association Analysis by Lasso Penalized Logistic Regression.
Bioinformatics, Volume 25, No 6, 714-721.
Supplementary Data
R package: CDLasso - Wu, T.T., Sun, W., Yuan, S., Chen, C.-H., and Li, K.-C. (2008) A Method for Analyzing Censored Survival Phenotype with Gene Expression Data. BMC Bioinformatics, Volume 9, 417.
- Wu, T.T. and Lange, K. (2008)
Coordinate Descent Algorithms for Lasso Penalized Regression.
Annals of Applied Statistics, Volume 2, No 1, 224-244.
Supplementary Appendix: Weak Consistency of Lasso Penalized l1 Regression
R package: CDLasso - Lange, K. and Wu, T.T. (2008)
An MM Algorithm for Multicategory Vertex Discriminant Analysis.
Journal of Computational and Graphical Statistics, Volume 17, No 3, 527-544.
Fortran 90 program and example
R package: VDA - Park, C.C., Ahn, S., Bloom, J.S., Lin, A., Wang, R.T., Wu, T.T., Sekar, A., Khan, A.H., Farr, C.J.,
Lusis, A.J., Leahy, R.M., Lange, K., and Smith, D. (2008)
Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids.
Nature Genetics, Volume 40, No 4, 421-429.
Supplementary information
Statistical Software
- R package: VDA (Vertex Discriminant Analysis)
A novel supervised multicategory classification method Reference1 Reference2
Can be installed in R or downloaded at CRAN Website - R package: CDLasso (Lasso Penalized Regression using Coordinate Descent Algorithms)
Lasso penalized L1, L2, and logistic regression Reference1 Reference2
Can be installed in R or downloaded at CRAN Website
Awards
- Research Support Award by UMCP (2009)
- Honored Faculty of 2nd Annual University-Wide Celebration of Scholarship and Research, UMCP (2009)
- Delta Omega (Alumni) by School of Public Health, UCLA (2008)
- International Travel Grant by the Office of International Programs, UMCP (2008)
Current Funding Support
- Co-Principal Investigator (lead PI: Edmund M. Clarke (CMU)), NSF Expeditions, 2009 - 2014
- Co-Investigator (PI: Stephen B. Thomas & Sandra Quinn (UMCP)), NIH P01, 2012 - 2017
- Co-Principal Investigator (PI: Yu Chen (UMCP)), NIH R21, 2012 - 2014
- Co-Investigator (PI: Yu Chen (UMCP)), NIH R21, 2011 - 2013
- Co-Investigator (PI: Yu Chen (UMCP)), NIH R21, 2011 - 2013
Useful Links
Blackboard
Terp Connect
SPH IT Repair Tickets