This course is a combination of group project, lecture, and seminar, covering a series of topics in Human-Computer Interaction (HCI) and Health Informatics, including design thinking, qualitative analysis, self-monitoring, health information visualization, clinician-patient communication, and patient engagement, etc. Due to the COVID-19, the course was devliered online. Each week, I provided a pre-recorded lecture and assigned related papers of the topic background. During the remote interaction sessions, students were engaged in seminar discussions and design exercise. Students had a chance to pitch ideas, collaborate with team members, and work on an interesting project over the course of 16 weeks. Following the spirit of human-centered design, we also spent part of our class time on brainstorming, providing critique, and sharing feedback. The aims of this course are to help students understand the unique challenges for designing patient-centered technologies, be aware of different types of digital health technologies currently available or being researched, and apply appropriate methods to design and evaluate patient-centered technologies. More details in Syllabus.